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ATLANTA — Results from a new post-hoc analysis of the previously presented VYtorin Versus Atorvastatin (VYVA) study of 1,902 patients with high cholesterol showed that a significantly greater number of patients taking VYTORIN(R) (ezetimibe/simvastatin) achieved levels of LDL ("bad&quo 
cholesterol of less than 70 mg/dl and Apolipoprotein B(1) (Apo B) levels of less than 90 mg/dL compared with patients taking Lipitor(R) pooled across the dosing range (p<0.001). The analysis also showed that a significantly greater number of patients taking VYTORIN reached levels of LDL cholesterol less than 70 mg/dL and C-Reactive Protein (CRP) levels less than 2 mg/L, compared with patients taking Lipitor pooled across the dosing range (p<0.001). This new analysis was presented today at the American College of Cardiology’s 55th Annual Scientific Session.
VYTORIN is indicated as adjunctive therapy to diet for the reduction of elevated total cholesterol, LDL cholesterol, Apo B, triglycerides and non-HDL cholesterol and to increase HDL cholesterol in patients with primary (heterozygous familial and non-familial) hypercholesterolemia or mixed hyperlipidemia. The active ingredients in VYTORIN are ezetimibe and simvastatin. VYTORIN is a prescription medicine and should not be taken by people who are hypersensitive to any of its components. VYTORIN should not be taken by anyone with active liver disease or unexplained persistent elevations of serum transaminases. Women who are of childbearing age (unless highly unlikely to conceive), are nursing or who are pregnant should not take VYTORIN.
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